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COSMETICGRADE CMOSTLY PRECLINICAL

GHK-Cu

Copper-binding tripeptide; collagen and remodelling signalling

A naturally occurring copper-binding tripeptide with a long record in skin research, where it is linked to collagen synthesis and wound remodelling. Topical cosmetic use is well established; injectable use is not.

ALSO KNOWN AS Copper tripeptide-1 · Gly-His-Lys copper
REGULATORY STATUS · COSMETIC USE

Widely used in topical cosmetics; injectable use is research-only.

§ EVIDENCE BASE
124
PUBLICATIONS
indexed in PubMed
3
REGISTERED TRIALS
listing it as an intervention
2
PHASE 2–4 TRIALS
reached later-stage testing
MECHANISMCopper-binding tripeptide; collagen and remodelling signalling
CATEGORYCosmetic
EVIDENCE GRADEC — Mostly preclinical
STATUSWidely used in topical cosmetics; injectable use is research-only
TYPICAL RECONSTITUTION50 mg vial + 5 mL BAC water (injectable)
ROUTESubcutaneous or topical
COUNTS RETRIEVED2026-07-23 · re-run the PubMed query
§ DOCUMENTED DOSING
Injectable1–2 mg per day
Topicalapply serum daily
Cycle4–8 weeks

Ranges compiled from published protocols, not a clinical guideline. Convert a dose into syringe units with the dosage calculator.

NOT MEDICAL ADVICE

This page summarises how much a compound has been studied. A high publication count is not evidence that something works, is safe, or is legal to obtain where you live. Consult a qualified healthcare provider before acting on anything here.

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