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PEPTIDE DECISION INTELLIGENCE
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PEPTIDE LIBRARY

Every peptide, on the record.

Mechanism, regulatory status, published research and registered trials for each compound — counted from the source registries, not estimated.

CATEGORY
EVIDENCE GRADE
§ 20 OF 20 PEPTIDES
METABOLICGRADE A

Semaglutide

GLP-1 receptor agonist

A long-acting GLP-1 receptor agonist given once weekly. It slows gastric emptying and acts on hypothalamic appetite signalling, and it carries th…

FDA-APPROVED5,214 PAPERS · 719 TRIALS
METABOLICGRADE A

Tirzepatide

Dual GIP / GLP-1 receptor agonist

A dual agonist hitting both the GIP and GLP-1 receptors. Head-to-head trials show greater average weight reduction than single-agonist GLP-1s, at…

FDA-APPROVED2,296 PAPERS · 264 TRIALS
GROWTH HORMONEGRADE A

Tesamorelin

GHRH analog

A stabilised growth-hormone-releasing hormone analog and the only approved GH secretagogue. Approved specifically to reduce excess visceral fat i…

FDA-APPROVED93 PAPERS · 24 TRIALS
IMMUNEGRADE B

LL-37

Cathelicidin antimicrobial peptide

The only human cathelicidin antimicrobial peptide, part of innate immune defence. Extensively characterised in immunology research; therapeutic u…

RESEARCH COMPOUND2,546 PAPERS · 20 TRIALS
RECOVERYGRADE B

Thymosin Beta-4

Actin-sequestering protein; cell migration and angiogenesis

The naturally occurring 43-amino-acid parent protein that TB-500 is derived from. It has been evaluated in registered trials for corneal and derm…

INVESTIGATIONAL684 PAPERS · 18 TRIALS
IMMUNEGRADE B

Thymosin Alpha-1

Immune modulator (T-cell maturation)

A 28-amino-acid immune-modulating peptide that promotes T-cell maturation. Used clinically in a number of countries as an adjunct in hepatitis B…

APPROVED OUTSIDE THE US626 PAPERS · 63 TRIALS
SEXUAL HEALTHGRADE B

PT-141

Melanocortin receptor agonist

A melanocortin receptor agonist acting on central pathways rather than on blood flow. Approved as bremelanotide for hypoactive sexual desire diso…

FDA-APPROVED112 PAPERS · 10 TRIALS
SLEEPGRADE C

DSIP

Delta sleep-inducing peptide; sleep architecture

A nonapeptide first isolated from rabbit cerebral venous blood during induced sleep. Named for its proposed effect on slow-wave sleep, though fin…

RESEARCH COMPOUND462 PAPERS · 1 TRIALS
LONGEVITYGRADE C

MOTS-c

Mitochondrial-derived peptide; AMPK activation

A mitochondrial-derived peptide that activates AMPK and is described in the literature as an exercise mimetic. Research is almost entirely precli…

RESEARCH COMPOUND246 PAPERS · 5 TRIALS
METABOLICGRADE C

Retatrutide

Triple GIP / GLP-1 / glucagon receptor agonist

An investigational triple agonist adding glucagon-receptor activity to the GIP/GLP-1 mechanism. Trial results to date report the largest average…

INVESTIGATIONAL158 PAPERS · 33 TRIALS
COSMETICGRADE C

GHK-Cu

Copper-binding tripeptide; collagen and remodelling signalling

A naturally occurring copper-binding tripeptide with a long record in skin research, where it is linked to collagen synthesis and wound remodelli…

COSMETIC USE124 PAPERS · 3 TRIALS
GROWTH HORMONEGRADE C

Ipamorelin

Selective ghrelin receptor agonist (GH secretagogue)

A pentapeptide GH secretagogue selective for the ghrelin receptor, so it raises growth hormone without the cortisol and prolactin rise seen with…

RESEARCH COMPOUND49 PAPERS · 3 TRIALS
RECOVERYGRADE D

BPC-157

Cytoprotective peptide; angiogenesis and growth-factor signalling

A synthetic pentadecapeptide derived from a sequence found in gastric juice. The preclinical record for tendon, ligament and gut-lining repair is…

RESEARCH COMPOUND214 PAPERS · 2 TRIALS
COGNITIVEGRADE D

Semax

ACTH(4-10) analog; BDNF modulation

A synthetic ACTH fragment analog without corticotropic activity, studied for neuroprotection and cognition. As with Selank, the evidence base is…

RESEARCH COMPOUND206 PAPERS · 0 TRIALS
LONGEVITYGRADE D

Epitalon

Tetrapeptide; telomerase and pineal regulation (proposed)

A synthetic tetrapeptide studied largely by a single research group for telomerase activation and circadian regulation. Independent replication i…

RESEARCH COMPOUND164 PAPERS · 0 TRIALS
RECOVERYGRADE D

KPV

α-MSH C-terminal tripeptide; anti-inflammatory

The C-terminal tripeptide of α-melanocyte-stimulating hormone, studied for anti-inflammatory activity in gut models without the pigmentation effe…

RESEARCH COMPOUND88 PAPERS · 0 TRIALS
COGNITIVEGRADE D

Selank

Anxiolytic heptapeptide (tuftsin analog)

A synthetic analog of the immunomodulatory peptide tuftsin, developed in Russia as an anxiolytic. Most of the published work originates from Russ…

RESEARCH COMPOUND68 PAPERS · 2 TRIALS
GROWTH HORMONEGRADE D

CJC-1295

GHRH analog (with or without DAC)

A GHRH analog that extends and amplifies natural growth-hormone pulses. The DAC version binds albumin for a much longer half-life. Commonly paire…

RESEARCH COMPOUND37 PAPERS · 1 TRIALS
RECOVERYGRADE D

TB-500

Actin-sequestering peptide (Thymosin β4 fragment)

A synthetic fragment corresponding to the actin-binding region of Thymosin β4. Marketed for systemic repair and often stacked with BPC-157. Most…

RESEARCH COMPOUND16 PAPERS · 1 TRIALS
METABOLICGRADE D

AOD-9604

hGH fragment 176-191; lipolytic activity (proposed)

A fragment of human growth hormone investigated as a fat-loss agent. Registered obesity trials did not show weight loss superior to placebo, and…

RESEARCH COMPOUND12 PAPERS · 0 TRIALS
§ HOW THE GRADES ARE SET

The grade is not a hand-assigned opinion. It is derived from the retrieved counts by a fixed rule, so it can be recomputed and checked:

AApproved for human use with a deep late-stage trial record
BApproved somewhere, or substantial late-stage human trials
CSome registered human trials or a large preclinical literature
DLittle or no registered human trial evidence

Publication and trial counts retrieved 2026-07-23 from PubMed and ClinicalTrials.gov. Trial counts include only studies listing the compound as an intervention. Each peptide page links the exact query used, so any figure here can be re-run at source.

Counts measure how much a compound has been studied — not whether it works, and not whether it is safe or legal to use.

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